Wrestling with God is never wrestling against Him (in the proper sense), but always for Him, that is, for His righteousness and justice, etc.  When Abraham and Moses wrestled with God they argued and pleaded for His righteousness and justice, and for His reputation (Gen. 18:22-32, Ex. 32:11-13).  Thus, our wrestling in prayer must always be against evil and on the side of God (though at times in prayer, when we can’t quite understand His will, we will find ourselves arguing against Him—until He shows us what is right).

When we wrestle with God, we wrestling to take hold of God; or we wrestle with ourselves, to arouse ourselves to take hold of God (Is. 64:7).  Our wrestling with God, in a sense, is trying to get God’s ear, or to get His attention.  It is a crying out to Him, a pleading with Him.  But all the while we must not try to convince Him of anything that is out of His will.  Hence, our wrestling must always be in harmony with the Spirit of prayer.

But let us not be content to just wait on Him—waiting for His will to play out.  No, we must take hold of God and plead for His will.  For that is what He really desires of us.  It is what the great men and women of faith did, and what we must do.