Abraham was one of the first great intercessors.  When God told him that He was going to destroy the city of Sodom, Abraham immediately became concerned for his cousin Lot, and for any others who were righteous in the city.

Genesis 18:23-33

And Abraham came near and said, “Wilt Thou indeed sweep away the righteous with the wicked? 24 “Suppose there are fifty righteous within the city; wilt Thou indeed sweep it away and not spare the place for the sake of the fifty righteous who are in it? 25 “Far be it from Thee to do such a thing, to slay the righteous with the wicked, so that the righteous and the wicked are treated alike. Far be it from Thee! Shall not the Judge of all the earth deal justly?” 26 So the Lord said, “If I find in Sodom fifty righteous within the city, then I…